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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • AMN 082 dihydrochloride EI0441

    AMN 082 dihydrochloride是首个选择性 mGlu7 激动剂。

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  • Amino活性的idine EI0437

    Amino活性的idine是H2 拮抗剂。

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  • AMG 548 EI0432

    AMG 548是活性的，选择性 p38α 抑制剂。

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  • AM 92016 hydrochloride EI0427

    AM 92016 hydrochloride是KV 通道阻断剂。

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  • AM 1172 EI0423

    AM 1172是Anandamide uptake inhibitor（摄取抑制剂）， 也是FAAH 抑制剂，CB 受体部分激动剂。

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