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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

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    AR-C 118925XX是选择性， 竞争性 P2Y2 受体拮抗剂。

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    Arachidonyl serotonin是Dual FAAH 抑制剂/TRPV1 拮抗剂。

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    AQ-RA 741是选择性， 高亲和性 M2 拮抗剂。

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