In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.
Apicidin是活性的HDAC (histone deacetylase) 抑制剂。
MoreAmthamine dihydrobromide是高选择性标准 H2 激动剂。
MoreAMN 082 dihydrochloride是首个选择性 mGlu7 激动剂。
MoreAmino活性的idine是H2 拮抗剂。
MoreAMG 548是活性的,选择性 p38α 抑制剂。
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