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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

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    Atiprimod dihydrochloride是JAK2 抑制剂。

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  • AS 2034178 EI0492

    AS 2034178是选择性 FFA1 (GPR40) 激动剂。

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  • AS 1892802 EI0490

    AS 1892802是活性的 ROCK 抑制剂， 口服有效。

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  • AS 1269574 EI0489

    AS 1269574是GPR119 受体激动剂。

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  • ARRY 520 trifluoroacetate EI0487

    ARRY 520 trifluoroacetate是活性的，选择性 kinesin spindle protein (KSP) 抑制剂， 诱导 Mcl-1 降解。

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