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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

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    AZ 12216052是 mGlu8的阳性变构调节剂。

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  • AZ 11645373 EI0513

    AZ 11645373是活性的，选择性 人 P2X7 拮抗剂。

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  • AZ 10606120 dihydrochloride EI0512

    AZ 10606120 dihydrochloride是活性的 P2X7 受体拮抗剂。

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  • AZ 10417808 EI0511

    AZ 10417808是选择性非肽类caspase-3 抑制剂。

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    ATPγS tetralithium salt是P2 激动剂， ATP类似物。。

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