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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

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    AZD 3988是活性的，选择性 DGAT-1 抑制剂。

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  • AZD 2066 EI0516

    AZD 2066是mGlu5 拮抗剂， 口服有效，。

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  • AZ 12216052 EI0515

    AZ 12216052是 mGlu8的阳性变构调节剂。

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  • AZ 11645373 EI0513

    AZ 11645373是活性的，选择性 人 P2X7 拮抗剂。

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  • AZ 10606120 dihydrochloride EI0512

    AZ 10606120 dihydrochloride是活性的 P2X7 受体拮抗剂。

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