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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

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    BAY-u 9773是CysLT1 和 CysLT2 拮抗剂。

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  • BAY-u 3405 EI0536

    BAY-u 3405是Dual TP/DP2 (CRTH2) 受体 拮抗剂。

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  • Bay 36-7620 EI0532

    Bay 36-7620是非竞争性 mGlu1 拮抗剂有反向激动剂活性。

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    AZD 9272是活性的，选择性 mGlu5 拮抗剂， 可透过血脑屏障。

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    AZD 7762 hydrochloride是Chk1，Chk2的活性选择性 ATP-竞争性抑制剂。

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