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COX


Cyclooxygenase (COX) is an enzyme (specifically, a family of isozymes) that is responsible for formation of prostanoids, including thromboxane and prostaglandins such as prostacyclin. Pharmaceutical inhibition of COX can provide relief from the symptoms of inflammation and pain. Nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin and ibuprofen, exert their effects through inhibition of COX. The two isozymes found in human are called COX-1 and COX-2 in the medical literature.

  • (S)-(+)-Ibuprofen EI0150

    (S)-(+)-Ibuprofen是Cyclooxygenase 抑制剂 (COX-1 > COX-2)。

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  • Tenidap EI2749

    Tenidap是NSAID， cyclooxygenase (COX-1) 抑制剂。 也是KIR2.3的开启剂。

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  • SC 58125 EI2503

    SC 58125是选择性 cyclooxygenase-2 (COX-2) 抑制剂。

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  • SC 236 EI2497

    SC 236是选择性 cyclooxygenase-2 (COX-2) 抑制剂。

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  • SC 560 EI2501

    SC 560是Cyclooxygenase-1 (COX-1) 抑制剂。

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