Dopamine Receptor
Dopamine receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system. The neurotransmitter dopamine is the primary endogenous ligand for dopamine receptors. Dopamine receptors are implicated in many neurological processes, including motivation, pleasure, cognition, memory, learning, and fine motor control, as well as modulation of neuroendocrine signaling. Abnormal dopamine receptor signaling and dopaminergic nerve function is implicated in several neuropsychiatric disorders. Thus, dopamine receptors are common neurologic drug targets; antipsychotics are often dopamine receptor antagonists while psychostimulants are typically indirect agonists of dopamine receptors. There are at least five subtypes of dopamine receptors, D1, D2, D3, D4, and D5. The D1 and D5 receptors are members of the D1-like family of dopamine receptors, whereas the D2, D3 and D4 receptors are members of the D2-like family.
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Domperidone是外周D2样受体拮抗剂(peripheral D2-like)。
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Dihydrexidine hydrochloride是选择性 D1样激动剂。
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D-Amphetamine sulfate是诱导dopamine， 5-HT，noradrenalin的释放。
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CY 208-243是选择性D1样激动剂。
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Clozapine是Dopamine 拮抗剂 具有部分 D4 选择性。 也是5-HT2A/2C 拮抗剂。
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Domperidone是外周D2样受体拮抗剂(peripheral D2-like)。
More
-
Dihydrexidine hydrochloride是选择性 D1样激动剂。
More
-
D-Amphetamine sulfate是诱导dopamine， 5-HT，noradrenalin的释放。
More
-
CY 208-243是选择性D1样激动剂。
More
-
Clozapine是Dopamine 拮抗剂 具有部分 D4 选择性。 也是5-HT2A/2C 拮抗剂。
More
