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Dopamine Receptor


Dopamine receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system. The neurotransmitter dopamine is the primary endogenous ligand for dopamine receptors. Dopamine receptors are implicated in many neurological processes, including motivation, pleasure, cognition, memory, learning, and fine motor control, as well as modulation of neuroendocrine signaling. Abnormal dopamine receptor signaling and dopaminergic nerve function is implicated in several neuropsychiatric disorders. Thus, dopamine receptors are common neurologic drug targets; antipsychotics are often dopamine receptor antagonists while psychostimulants are typically indirect agonists of dopamine receptors.  There are at least five subtypes of dopamine receptors, D1, D2, D3, D4, and D5. The D1 and D5 receptors are members of the D1-like family of dopamine receptors, whereas the D2, D3 and D4 receptors are members of the D2-like family. 
  • GBR 12783 dihydrochloride EI1173

    GBR 12783 dihydrochloride是活性选择性 dopamine uptake inhibitor(摄取抑制剂)。

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  • Flupenthixol dihydrochloride EI1131

    Flupenthixol dihydrochloride是Dopamine 受体拮抗剂。

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  • Fenoldopam hydrochloride EI1112

    Fenoldopam hydrochloride是选择性 D1样部分激动剂。

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  • Fananserin EI1108

    Fananserin是5-HT2A 拮抗剂。 也是D4 拮抗剂。

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  • Eticlopride hydrochloride EI1101

    Eticlopride hydrochloride是选择性 D2/D3 拮抗剂。

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  • GBR 12783 dihydrochloride EI1173

    GBR 12783 dihydrochloride是活性选择性 dopamine uptake inhibitor(摄取抑制剂)。

    More
  • Flupenthixol dihydrochloride EI1131

    Flupenthixol dihydrochloride是Dopamine 受体拮抗剂。

    More
  • Fenoldopam hydrochloride EI1112

    Fenoldopam hydrochloride是选择性 D1样部分激动剂。

    More
  • Fananserin EI1108

    Fananserin是5-HT2A 拮抗剂。 也是D4 拮抗剂。

    More
  • Eticlopride hydrochloride EI1101

    Eticlopride hydrochloride是选择性 D2/D3 拮抗剂。

    More
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