Dopamine Receptor
Dopamine receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system. The neurotransmitter dopamine is the primary endogenous ligand for dopamine receptors. Dopamine receptors are implicated in many neurological processes, including motivation, pleasure, cognition, memory, learning, and fine motor control, as well as modulation of neuroendocrine signaling. Abnormal dopamine receptor signaling and dopaminergic nerve function is implicated in several neuropsychiatric disorders. Thus, dopamine receptors are common neurologic drug targets; antipsychotics are often dopamine receptor antagonists while psychostimulants are typically indirect agonists of dopamine receptors. There are at least five subtypes of dopamine receptors, D1, D2, D3, D4, and D5. The D1 and D5 receptors are members of the D1-like family of dopamine receptors, whereas the D2, D3 and D4 receptors are members of the D2-like family.
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Pergolide是有抗帕金森病特性的多巴胺受体激动剂。
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Benzotropine是抗毒蕈碱的化合物，多巴胺转运蛋白抑制剂，IC50为118 nM，可辅助治疗帕金森病。
More
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Pramipexole是多巴胺受体激动剂，对帕金森综合症和腿多动综合征有效。
More
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Pergolide是有抗帕金森病特性的多巴胺受体激动剂。
More
-
Benzotropine是抗毒蕈碱的化合物，多巴胺转运蛋白抑制剂，IC50为118 nM，可辅助治疗帕金森病。
More
-
Pramipexole是多巴胺受体激动剂，对帕金森综合症和腿多动综合征有效。
More
