Dopamine Receptor
Dopamine receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system. The neurotransmitter dopamine is the primary endogenous ligand for dopamine receptors. Dopamine receptors are implicated in many neurological processes, including motivation, pleasure, cognition, memory, learning, and fine motor control, as well as modulation of neuroendocrine signaling. Abnormal dopamine receptor signaling and dopaminergic nerve function is implicated in several neuropsychiatric disorders. Thus, dopamine receptors are common neurologic drug targets; antipsychotics are often dopamine receptor antagonists while psychostimulants are typically indirect agonists of dopamine receptors. There are at least five subtypes of dopamine receptors, D1, D2, D3, D4, and D5. The D1 and D5 receptors are members of the D1-like family of dopamine receptors, whereas the D2, D3 and D4 receptors are members of the D2-like family.
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L-741，742 hydrochloride是高选择性 D4 拮抗剂。
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L-745，870 trihydrochloride是高选择性 D4 拮抗剂。
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JHW 007 hydrochloride是高亲和性 dopamine uptake inhibitor（摄取抑制剂）。
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Indatraline hydrochloride是活性的 5-HT uptake inhibitor（摄取抑制剂）， 也抑制 dopamine，noradrenalin的吸收。
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Chlorpromazine hydrochloride (盐酸氯丙嗪) 是多巴胺受体和钾离子通道抑制剂。
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L-741，742 hydrochloride是高选择性 D4 拮抗剂。
More
-
L-745，870 trihydrochloride是高选择性 D4 拮抗剂。
More
-
JHW 007 hydrochloride是高亲和性 dopamine uptake inhibitor（摄取抑制剂）。
More
-
Indatraline hydrochloride是活性的 5-HT uptake inhibitor（摄取抑制剂）， 也抑制 dopamine，noradrenalin的吸收。
More
-
Chlorpromazine hydrochloride (盐酸氯丙嗪) 是多巴胺受体和钾离子通道抑制剂。
More
