Home > Signal Pathway > GPCR & G Protein > Dopamine Receptor

Dopamine Receptor


Dopamine receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system. The neurotransmitter dopamine is the primary endogenous ligand for dopamine receptors. Dopamine receptors are implicated in many neurological processes, including motivation, pleasure, cognition, memory, learning, and fine motor control, as well as modulation of neuroendocrine signaling. Abnormal dopamine receptor signaling and dopaminergic nerve function is implicated in several neuropsychiatric disorders. Thus, dopamine receptors are common neurologic drug targets; antipsychotics are often dopamine receptor antagonists while psychostimulants are typically indirect agonists of dopamine receptors.  There are at least five subtypes of dopamine receptors, D1, D2, D3, D4, and D5. The D1 and D5 receptors are members of the D1-like family of dopamine receptors, whereas the D2, D3 and D4 receptors are members of the D2-like family. 
  • NPEC键和的dopamine EI1929

    NPEC键和的dopamine是1-(2-nitrophenyl)ethoxycarbonyl 基团键和的dopamine。

    More
  • Nomifensine EI1914

    Nomifensine是活性的去甲肾上腺素、多巴胺的摄取抑制剂(uptake inhibitor)。抗抑郁剂。

    More
  • NGD 94-1 EI1885

    NGD 94-1是选择性 D4 受体配体。

    More
  • NGB 2904 EI1884

    NGB 2904是活性的,选择性 D3 拮抗剂。

    More
  • Nemonapride EI1852

    Nemonapride是高 活性的 D2样拮抗剂。 也是5-HT1A 激动剂。

    More
  • NPEC键和的dopamine EI1929

    NPEC键和的dopamine是1-(2-nitrophenyl)ethoxycarbonyl 基团键和的dopamine。

    More
  • Nomifensine EI1914

    Nomifensine是活性的去甲肾上腺素、多巴胺的摄取抑制剂(uptake inhibitor)。抗抑郁剂。

    More
  • NGD 94-1 EI1885

    NGD 94-1是选择性 D4 受体配体。

    More
  • NGB 2904 EI1884

    NGB 2904是活性的,选择性 D3 拮抗剂。

    More
  • Nemonapride EI1852

    Nemonapride是高 活性的 D2样拮抗剂。 也是5-HT1A 激动剂。

    More
  • Current page15, Total Pages20, Total Record98 First Prev 1314151617 Next Last Goto