Dopamine Receptor
Dopamine receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system. The neurotransmitter dopamine is the primary endogenous ligand for dopamine receptors. Dopamine receptors are implicated in many neurological processes, including motivation, pleasure, cognition, memory, learning, and fine motor control, as well as modulation of neuroendocrine signaling. Abnormal dopamine receptor signaling and dopaminergic nerve function is implicated in several neuropsychiatric disorders. Thus, dopamine receptors are common neurologic drug targets; antipsychotics are often dopamine receptor antagonists while psychostimulants are typically indirect agonists of dopamine receptors. There are at least five subtypes of dopamine receptors, D1, D2, D3, D4, and D5. The D1 and D5 receptors are members of the D1-like family of dopamine receptors, whereas the D2, D3 and D4 receptors are members of the D2-like family.
-
Quetiapine hemifumarate是5-HT2/D2 拮抗剂具有抗精神病活性（atypical antipsychotic）。
More
-
Prochlorperazine dimaleate是D2 受体拮抗剂。 也是5-HT3 和 nAChR 的拮抗剂。
More
-
Pramipexole dihydrochloride是选择性D3激动剂。
More
-
PNU 177864 hydrochloride是高选择性 D3 拮抗剂。
More
-
Pimozide是D2样拮抗剂。
More
-
Quetiapine hemifumarate是5-HT2/D2 拮抗剂具有抗精神病活性（atypical antipsychotic）。
More
-
Prochlorperazine dimaleate是D2 受体拮抗剂。 也是5-HT3 和 nAChR 的拮抗剂。
More
-
Pramipexole dihydrochloride是选择性D3激动剂。
More
-
PNU 177864 hydrochloride是高选择性 D3 拮抗剂。
More
-
Pimozide是D2样拮抗剂。
More
