Dopamine Receptor
Dopamine receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system. The neurotransmitter dopamine is the primary endogenous ligand for dopamine receptors. Dopamine receptors are implicated in many neurological processes, including motivation, pleasure, cognition, memory, learning, and fine motor control, as well as modulation of neuroendocrine signaling. Abnormal dopamine receptor signaling and dopaminergic nerve function is implicated in several neuropsychiatric disorders. Thus, dopamine receptors are common neurologic drug targets; antipsychotics are often dopamine receptor antagonists while psychostimulants are typically indirect agonists of dopamine receptors. There are at least five subtypes of dopamine receptors, D1, D2, D3, D4, and D5. The D1 and D5 receptors are members of the D1-like family of dopamine receptors, whereas the D2, D3 and D4 receptors are members of the D2-like family.
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Spiperone hydrochloride是5-HT2A 拮抗剂。 也是D2样受体拮抗剂。
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Sonepiprazole是选择性 D4 受体拮抗剂。
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SKF 38393 hydrobromide是选择性 D1样激动剂。
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SCH 39166 hydrobromide是高亲和性 D1/D5 受体拮抗剂。
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SCH 23390 hydrochloride是经典的选择性 D1样拮抗剂， 也是5-HT2C和5-HT1C的激动剂，Kir3的通道阻断剂。
More
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Spiperone hydrochloride是5-HT2A 拮抗剂。 也是D2样受体拮抗剂。
More
-
Sonepiprazole是选择性 D4 受体拮抗剂。
More
-
SKF 38393 hydrobromide是选择性 D1样激动剂。
More
-
SCH 39166 hydrobromide是高亲和性 D1/D5 受体拮抗剂。
More
-
SCH 23390 hydrochloride是经典的选择性 D1样拮抗剂， 也是5-HT2C和5-HT1C的激动剂，Kir3的通道阻断剂。
More
