Home > Signal Pathway > GPCR & G Protein > Dopamine Receptor

Dopamine Receptor


Dopamine receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system. The neurotransmitter dopamine is the primary endogenous ligand for dopamine receptors. Dopamine receptors are implicated in many neurological processes, including motivation, pleasure, cognition, memory, learning, and fine motor control, as well as modulation of neuroendocrine signaling. Abnormal dopamine receptor signaling and dopaminergic nerve function is implicated in several neuropsychiatric disorders. Thus, dopamine receptors are common neurologic drug targets; antipsychotics are often dopamine receptor antagonists while psychostimulants are typically indirect agonists of dopamine receptors.  There are at least five subtypes of dopamine receptors, D1, D2, D3, D4, and D5. The D1 and D5 receptors are members of the D1-like family of dopamine receptors, whereas the D2, D3 and D4 receptors are members of the D2-like family. 
  • Ziprasidone hydrochloride EI3002

    Ziprasidone hydrochloride是5-HT2A/D2 拮抗剂, atypical antipsychotic。

    More
  • U 99194 maleate EI2835

    U 99194 maleate是活性的选择性 D3 拮抗剂。

    More
  • Threo-methylphenidate hydrochloride EI2777

    Threo-methylphenidate hydrochloride是Dopamine,noradrenalin transporters的抑制剂 。 精神运动性兴奋(Psychomotor stimulant)。

    More
  • Thioridazine hydrochloride EI2772

    Thioridazine hydrochloride是Dopamine受体拮抗剂,抗精神病药物antipsychotic。

    More
  • Sumanirole maleate EI2650

    Sumanirole maleate是D2受体的选择性激动剂。

    More
  • Ziprasidone hydrochloride EI3002

    Ziprasidone hydrochloride是5-HT2A/D2 拮抗剂, atypical antipsychotic。

    More
  • U 99194 maleate EI2835

    U 99194 maleate是活性的选择性 D3 拮抗剂。

    More
  • Threo-methylphenidate hydrochloride EI2777

    Threo-methylphenidate hydrochloride是Dopamine,noradrenalin transporters的抑制剂 。 精神运动性兴奋(Psychomotor stimulant)。

    More
  • Thioridazine hydrochloride EI2772

    Thioridazine hydrochloride是Dopamine受体拮抗剂,抗精神病药物antipsychotic。

    More
  • Sumanirole maleate EI2650

    Sumanirole maleate是D2受体的选择性激动剂。

    More
  • Current page10, Total Pages20, Total Record98 First Prev 89101112 Next Last Goto