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5-HT Receptor


5-HT receptors (5-hydroxytryptamine receptors,The serotonin receptors) are a group of G protein-coupled receptors (GPCRs) and ligand-gated ion channels (LGICs) found in the central and peripheral nervous systems. They mediate both excitatory and inhibitory neurotransmission. The serotonin receptors are activated by the neurotransmitter serotonin, which acts as their natural ligand.

  • Almotriptan Malate EY1684

    Almotriptan malate是5-HT1B/1D受体激动剂，可作用于偏头疼。

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  • WAY-100635 Maleate EY1659

    WAY-100635 Maleate是一种有效的，选择性的5-HT1A受体激动剂，pIC50为8.87，比作用于其他5-HT受体亚型和主要的神经递质受体选择性高100倍以上。

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  • Urapidil HCl EY1565

    Urapidil HCl是Urapidil的盐酸盐形式，是α1-肾上腺素能受体拮抗剂和5-HT1A受体激动剂，pIC50分别为6.13和6.4。

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  • Escitalopram Oxalate EY1510

    Escitalopram oxalate是选择性5羟色胺重吸收抑制剂（SSRI），Ki为0.89 nM。

    More

  • Sumatriptan Succinate EY1445

    Sumatriptan succinate是5-HT1受体激动剂，可作用于偏头疼。

    More

  • Almotriptan Malate EY1684

    Almotriptan malate是5-HT1B/1D受体激动剂，可作用于偏头疼。

    More

  • WAY-100635 Maleate EY1659

    WAY-100635 Maleate是一种有效的，选择性的5-HT1A受体激动剂，pIC50为8.87，比作用于其他5-HT受体亚型和主要的神经递质受体选择性高100倍以上。

    More

  • Urapidil HCl EY1565

    Urapidil HCl是Urapidil的盐酸盐形式，是α1-肾上腺素能受体拮抗剂和5-HT1A受体激动剂，pIC50分别为6.13和6.4。

    More

  • Escitalopram Oxalate EY1510

    Escitalopram oxalate是选择性5羟色胺重吸收抑制剂（SSRI），Ki为0.89 nM。

    More

  • Sumatriptan Succinate EY1445

    Sumatriptan succinate是5-HT1受体激动剂，可作用于偏头疼。

    More
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