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5-HT Receptor


5-HT receptors (5-hydroxytryptamine receptors,The serotonin receptors) are a group of G protein-coupled receptors (GPCRs) and ligand-gated ion channels (LGICs) found in the central and peripheral nervous systems. They mediate both excitatory and inhibitory neurotransmission. The serotonin receptors are activated by the neurotransmitter serotonin, which acts as their natural ligand.

  • Indatraline hydrochloride EI1348

    Indatraline hydrochloride是活性的 5-HT uptake inhibitor（摄取抑制剂）， 也抑制 dopamine，noradrenalin的吸收。

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  • RS-127445 EY1668

    RS-127445(MT 500)是5-HT2B受体拮抗剂，pKi和pIC50分别为9.5和10.4。

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  • Ketanserin EY1297

    Ketanserin 是一种特异性的5-HT2A 5-羟色胺受体拮抗剂，作用于大鼠和人5-HT2A，Ki为2.5 nM。

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  • Olanzapine EY0717

    Olanzapine是5-HT2和D2受体高亲和性拮抗剂。

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  • Aripiprazole EY1816

    Aripiprazole是一种人5-HT1A受体激动剂，Ki为4.2 nM。

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  • Indatraline hydrochloride EI1348

    Indatraline hydrochloride是活性的 5-HT uptake inhibitor（摄取抑制剂）， 也抑制 dopamine，noradrenalin的吸收。

    More

  • RS-127445 EY1668

    RS-127445(MT 500)是5-HT2B受体拮抗剂，pKi和pIC50分别为9.5和10.4。

    More

  • Ketanserin EY1297

    Ketanserin 是一种特异性的5-HT2A 5-羟色胺受体拮抗剂，作用于大鼠和人5-HT2A，Ki为2.5 nM。

    More

  • Olanzapine EY0717

    Olanzapine是5-HT2和D2受体高亲和性拮抗剂。

    More

  • Aripiprazole EY1816

    Aripiprazole是一种人5-HT1A受体激动剂，Ki为4.2 nM。

    More
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