Adrenergic Receptor
The adrenergic receptors (or adrenoceptors) are a class of G protein-coupled receptors that are targets of the catecholamines, especially norepinephrine (noradrenaline) and epinephrine (adrenaline). Epinephrine (adrenaline) reacts with both α- and β-adrenoreceptors, causing vasoconstriction and vasodilation, respectively. High levels of circulating epinephrine cause vasoconstriction. At lower levels of circulating epinephrine, β-adrenoreceptor stimulation dominates, producing vasodilation followed by decrease of peripheral vascular resistance.
Many cells possess these receptors, and the binding of a catecholamine to the receptor will generally stimulate the sympathetic nervous system. The sympathetic nervous system is responsible for the fight-or-flight response, which includes dilating the pupils, increasing heart rate, mobilizing energy, and diverting blood flow from non-essential organs to skeletal muscle.
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Atipamezole hydrochloride是选择性 α2 拮抗剂。
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ARC 239 dihydrochloride是α2B 拮抗剂。
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AH 11110 hydrochloride是亚型选择性 α1B 配体。
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Agmatine sulfate是α2 配体。 也是imidazoline 配体。
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A 80426 mesylate是高亲和性 α2 拮抗剂。 也是 5-HT uptake inhibitor（摄取抑制剂）。
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Atipamezole hydrochloride是选择性 α2 拮抗剂。
More
-
ARC 239 dihydrochloride是α2B 拮抗剂。
More
-
AH 11110 hydrochloride是亚型选择性 α1B 配体。
More
-
Agmatine sulfate是α2 配体。 也是imidazoline 配体。
More
-
A 80426 mesylate是高亲和性 α2 拮抗剂。 也是 5-HT uptake inhibitor（摄取抑制剂）。
More
