Adrenergic Receptor
The adrenergic receptors (or adrenoceptors) are a class of G protein-coupled receptors that are targets of the catecholamines, especially norepinephrine (noradrenaline) and epinephrine (adrenaline). Epinephrine (adrenaline) reacts with both α- and β-adrenoreceptors, causing vasoconstriction and vasodilation, respectively. High levels of circulating epinephrine cause vasoconstriction. At lower levels of circulating epinephrine, β-adrenoreceptor stimulation dominates, producing vasodilation followed by decrease of peripheral vascular resistance.
Many cells possess these receptors, and the binding of a catecholamine to the receptor will generally stimulate the sympathetic nervous system. The sympathetic nervous system is responsible for the fight-or-flight response, which includes dilating the pupils, increasing heart rate, mobilizing energy, and diverting blood flow from non-essential organs to skeletal muscle.
-
Salbutamol Sulfate是一种短效的β2-肾上腺素能受体激动剂，IC50为8.93 µM。
More
-
Bisoprolol是β1肾上腺素受体阻断剂。
More
-
Prazosin hydrochloride是α肾上腺素阻断剂，可作用于高血压、焦虑和恐慌症等。
More
-
Dexmedetomidine 是α2肾上腺素受体激动剂，有止痛镇静活性。
More
-
Formoterol Fumarate是长效的β2-肾上腺素受体激动剂。
More
-
Salbutamol Sulfate是一种短效的β2-肾上腺素能受体激动剂，IC50为8.93 µM。
More
-
Bisoprolol是β1肾上腺素受体阻断剂。
More
-
Prazosin hydrochloride是α肾上腺素阻断剂，可作用于高血压、焦虑和恐慌症等。
More
-
Dexmedetomidine 是α2肾上腺素受体激动剂，有止痛镇静活性。
More
-
Formoterol Fumarate是长效的β2-肾上腺素受体激动剂。
More
