Adrenergic Receptor
The adrenergic receptors (or adrenoceptors) are a class of G protein-coupled receptors that are targets of the catecholamines, especially norepinephrine (noradrenaline) and epinephrine (adrenaline). Epinephrine (adrenaline) reacts with both α- and β-adrenoreceptors, causing vasoconstriction and vasodilation, respectively. High levels of circulating epinephrine cause vasoconstriction. At lower levels of circulating epinephrine, β-adrenoreceptor stimulation dominates, producing vasodilation followed by decrease of peripheral vascular resistance.
Many cells possess these receptors, and the binding of a catecholamine to the receptor will generally stimulate the sympathetic nervous system. The sympathetic nervous system is responsible for the fight-or-flight response, which includes dilating the pupils, increasing heart rate, mobilizing energy, and diverting blood flow from non-essential organs to skeletal muscle.
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L-748，337是选择性 β3 拮抗剂。
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JP 1302 dihydrochloride是活性选择性 α2C 拮抗剂。
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Imiloxan hydrochloride是高选择性α2B拮抗剂。
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Isoprenaline hydrochloride是非选择性的β-肾上腺素受体激动剂，与肾上腺素相似。
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Doxazosin mesylate能选择性拮抗突触后的α1肾上腺素受体。
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-
L-748，337是选择性 β3 拮抗剂。
More
-
JP 1302 dihydrochloride是活性选择性 α2C 拮抗剂。
More
-
Imiloxan hydrochloride是高选择性α2B拮抗剂。
More
-
Isoprenaline hydrochloride是非选择性的β-肾上腺素受体激动剂，与肾上腺素相似。
More
-
Doxazosin mesylate能选择性拮抗突触后的α1肾上腺素受体。
More
