Adrenergic Receptor
The adrenergic receptors (or adrenoceptors) are a class of G protein-coupled receptors that are targets of the catecholamines, especially norepinephrine (noradrenaline) and epinephrine (adrenaline). Epinephrine (adrenaline) reacts with both α- and β-adrenoreceptors, causing vasoconstriction and vasodilation, respectively. High levels of circulating epinephrine cause vasoconstriction. At lower levels of circulating epinephrine, β-adrenoreceptor stimulation dominates, producing vasodilation followed by decrease of peripheral vascular resistance.
Many cells possess these receptors, and the binding of a catecholamine to the receptor will generally stimulate the sympathetic nervous system. The sympathetic nervous system is responsible for the fight-or-flight response, which includes dilating the pupils, increasing heart rate, mobilizing energy, and diverting blood flow from non-essential organs to skeletal muscle.
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(S)-(-)-Pindolol是β3 部分 激动剂。Pindolol的对映体之一。
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(S)-(-)-Atenolol是β1-拮抗剂。Atenolol的活性异构体。
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(RS)-Atenolol是β1 拮抗剂。
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(R)-(-)-Niguldipine hydrochloride是α1 拮抗剂， L-type Ca2+ 通道阻断剂。Niguldipine hydrochloride的对映体之一。
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Olodaterol 是长效的β2-adrenoceptor激动剂，EC50=1.4±0.08 nM。
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(S)-(-)-Pindolol是β3 部分 激动剂。Pindolol的对映体之一。
More
-
(S)-(-)-Atenolol是β1-拮抗剂。Atenolol的活性异构体。
More
-
(RS)-Atenolol是β1 拮抗剂。
More
-
(R)-(-)-Niguldipine hydrochloride是α1 拮抗剂， L-type Ca2+ 通道阻断剂。Niguldipine hydrochloride的对映体之一。
More
-
Olodaterol 是长效的β2-adrenoceptor激动剂，EC50=1.4±0.08 nM。
More
