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Opioid Receptor


Opioid receptors are a group of inhibitory G protein-coupled receptors with opioids as ligands.[1][2][3] The endogenous opioids are dynorphins, enkephalins, endorphins, endomorphins and nociceptin. The opioid receptors are ~40% identical to somatostatin receptors (SSTRs). Opioid receptors are distributed widely in the brain, and are found in the spinal cord and digestive tract.The endogenous opioid system is thought to be important in mediating complex social behaviors involved in the formation of stable, emotionally committed relationships.

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    ADL5859是δ-阿片受体选择性激动剂，Ki为0.8 nM，对hERG有弱抑制性。

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    Loperamide hydrochloride是阿片类受体激动剂，是长效止泻剂。

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  • ADL5859 HCl EY0445

    ADL5859是δ-阿片受体选择性激动剂，Ki为0.8 nM，对hERG有弱抑制性。

    More

  • Loperamide HCl EY1268

    Loperamide hydrochloride是阿片类受体激动剂，是长效止泻剂。

    More

  • ADL5859 HCl EY0445

    ADL5859是δ-阿片受体选择性激动剂，Ki为0.8 nM，对hERG有弱抑制性。

    More
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