FT-207 (NSC 148958) is a substance being used in the treatment of some types of cancer.
MoreEtodolac, a member of non steroidal anti-inflammatory drugs (NSAIDs), has a poor aqueous solubility. Etodolac (Lodine) is a COX inhibitor with an IC50 of 53.5 nM.
MoreClofarabine is a potent HIV-1 inhibitor in both activated CD4+ T cells and macrophages. Clofarabine inhibits the enzymatic activities of ribonucleotide reductase (IC50 = 65 nM) and DNA polymerase
MoreTamoxifen is a selective estrogen receptor (ER) modulator. Tamoxifen-induced apoptosis was associated with inhibition of cancerous inhibitor of protein phosphatase 2A (CIP2A) and phospho-Akt (p-Akt) in a dose-dependent manner.
MoreDienogest(STS-557) is a specific progesterone receptor agonist with potent oral endometrial activity and is used in the treatment of endometriosis. Dienogest is a hybrid progestin possessing characteristics both of 19-nortestosterone derivatives and progesterone derivatives.
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