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Tizanidine HCl is a skeletal muscle relaxant. It is an α2-adrenergic receptor agonist and inhibits neurotransmitter release from CNS noradrenergic neurons.
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Carmofur, a derivative of 5-fluorouracil (5-FU), has been widely used in Japan as a postoperative adjuvant chemotherapy agent for colorectal and breast cancer.
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FT-207 (NSC 148958) is a substance being used in the treatment of some types of cancer.
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Etodolac, a member of non steroidal anti-inflammatory drugs (NSAIDs), has a poor aqueous solubility. Etodolac (Lodine) is a COX inhibitor with an IC50 of 53.5 nM.
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Clofarabine is a potent HIV-1 inhibitor in both activated CD4+ T cells and macrophages. Clofarabine inhibits the enzymatic activities of ribonucleotide reductase (IC50 = 65 nM) and DNA polymerase
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