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Aminoglutethimide is an aromatase inhibitor with IC50 of 10 μM.
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Silodosin(Rapaflo) is an α1-adrenoceptor antagonist with high uroselectivity. Silodosin causes practically no orthostatic hypotension (in contrast to other α1 blockers). Since Silodosin is a highly selective inhibitor of the α1A adrenergic receptor, it causes practically no orthostatic hypotension (in contrast to other α1 blockers).
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Ethynyl estradiol is an orally bio-active estrogen used in almost all modern formulations of combined oral contraceptive pills.
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Acetaminophen is a inhibitor of Cox-1, Cox-2, and Cox-3 (cyclooxygenase) . Acetaminophen may be selective for Cox-3 (IC50 values are > 1000, > 1000, and 460 μM for murine Cox-1, murine Cox-2, and canine Cox-3, respectively). Acetaminophen is a widely used analgesic and antipyretic agent.
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Gestodene is a progestogen hormonal contraceptive. Gestodene is a novel synthetic progestin--characterization of binding to receptor and serum proteins.
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