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Acetaminophen is a inhibitor of Cox-1, Cox-2, and Cox-3 (cyclooxygenase) . Acetaminophen may be selective for Cox-3 (IC50 values are > 1000, > 1000, and 460 μM for murine Cox-1, murine Cox-2, and canine Cox-3, respectively). Acetaminophen is a widely used analgesic and antipyretic agent.
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Gestodene is a progestogen hormonal contraceptive. Gestodene is a novel synthetic progestin--characterization of binding to receptor and serum proteins.
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Drospirenone is a ourth-generation and synthetic progestogen exhibiting antiandrogenic and antimineralocorticoid activity.
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Pizotifen is an antagonist of muscarinic receptors and a serotonin antagonist acting mainly at the 5-HT1, 5-HT2A and 5HT2C receptors with some antihistamine activity.
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Rocuronium Bromide is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia, to facilitate endotracheal intubation and to provide skeletal musclerelaxation during surgery or mechanical ventilation.
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