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  • FAK Inhibitor 14 EY2034

    FAK Inhibitor 14 is a selective focal adhesion kinase (FAK) inhibitor, it prevents FAK autophosphorylation at Y397 (IC50 = 1μM).

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  • ML-167 EY2030

    ML167 is the first highly selective inhibitor of of Cdc2-like kinase 4 (Clk4) with an IC50 of 136 nM for Clk4, >10-fold selectivity for closely related kinases Clk1-3 and Dyrk1A/1B, and minimal activity against a panel of other kinases tested.

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  • NS-398 EY2015

    NS-398是一种COX-2抑制剂,抑制作用呈浓度依赖性。100μM NS-398不影响COX-1活性, 而抑制COX-2活性(IC50: 3.8 μM)。

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  • Ac-YVAD-CMK EY2016

    Ac-Tyr-Val-Ala-Asp-CMK is a cell-permeable and irreversible inhibitor of caspase-1 (Ki = 760 pM), caspase-4, and caspase-5.

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  • Caspase-1 inhibitor-I EY2017

    A cell-permeable inhibitor of caspase-1, caspase-4, and caspase-5.

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