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  • Fludarabine EY0005

    Fludarabine, a purine analog, is used in the treatment of hematological malignancies for the inhibition of STAT-1 activation and DNA synthesis. Fludarabine是一种STAT1活性抑制剂和DNA合成抑制剂。

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  • Lapatinib EY0007

    Lapatinib (GW572016) is a small-molecule dual inhibitor of EGFR and ErbB2 receptor kinase activities. Lapatinib可形成Lapatinib的二甲苯磺酸盐，是一种有效的EGFR和ErbB2抑制剂，IC50分别为10.2和9.8 nM。

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  • Rapamycin EY0008

    Rapamycin, an mTOR inhibitor, shows potent immunosuppressive and antiproliferative properties. Rapamycin是一种常用的选择性的mTOR抑制剂，IC50为~0.1 nM。

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  • MG-132 EY0002

    MG-132是一种蛋白酶体抑制剂，IC50为100 nM。还能抑制钙蛋白酶，IC50为1.2 μM。

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  • Ketoprofen EY2220

    Ketoprofen is a non-selective NSAID with IC50 of 0.5 μM and 2.33 μM for human recombinant COX-1 and COX-2, respectively.

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