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Obinutuzumab (Gazyva) is a unique, third-generation, fully humanized glycoengineered IgG1 type II anti-CD20 monoclonal antibody monoclonal antibody, approved in chronic lymphocytic leukemia (B-CLL) and follicular lymphoma (FL).
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Ofatumumab, a humanized anti-CD20 monoclonal antibody, has been proven to be effective in the treatment of relapsed, refractory CLL.
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Omalizumab (rhuMAb-E25), an anti-IgE antibody, inhibits the interaction between IgE and FcϵRI, is the first targeted biologic therapeutic approved for the treatment of moderate-to-severe persistent allergic asthma (AA).
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Palivizumab, a humanized murine monoclonal antibody, is the only prophylactic agent approved for respiratory syncytial virus (RSV).
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Panitumumab, a fully human and less immunogenic anti-EGFR monoclonal antibody, is widely used in patients with metastatic colorectal cancer.
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