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  • Quisinostat EY2222

    Quisinostat (JNJ-26481585) is a novel second-generation HDACi inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM, modest potent to HDACs 2, 4, 10, and 11; greater than 30-fold selectivity against HDACs 3, 5, 8, and 9 and lowest potency to HDACs 6 and 7. , in NSCLC cells. In vitro, quisinostat has shown anti-proliferative activity against NSCLC cell lines. quisinostat extremely changed protein acetylation patterns of A549 cells and inhibited epithelial-mesenchymal transition (EMT) process.

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  • IDRA 21 EI1335

    IDRA 21是抑制 AMPA 受体脱敏（inhibit desensitization)。

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  • IEM 1460 EI1336

    IEM 1460是IEM 1460 is an AMPA currents' open-channel blocker and selective for non-GluR2-containing receptors.。

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  • ICI 162，846 EI1328

    ICI 162，846是活性的 H2 拮抗剂， 体内有效。

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  • Ibotenic acid EI1319

    Ibotenic acid是非选择性 NMDA 激动剂。

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