Naringenin, a common dietary flavonoid abundantly present in fruits and vegetables, is believed to possess strong anti-proliferative properties and the ability to induce apoptosis in hepatoma cell lines.
MoreAZ20是高活性ATR抑制剂,IC50为5 nM,对mTOR的IC50为38 nM。
MoreGSK2636771是一种口服生物有效的PI3Kβ选择性抑制剂,对PTEN缺失细胞系敏感。
MoreAmuvatinib (MP-470)是多靶点抑制剂,对c-Kit(D816H),PDGFRα(V561D)和FLT3(D835Y)的IC50分别为10 nM,40 nM和81 nM。
MoreLY2940680能结合Smoothened (Smo)受体,并抑制Hedgehog (Hh)信号传导。
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