Vorinostat (SAHA, MK0683)是一种I和II类组蛋白去乙酰化酶(HDAC)抑制剂,IC50小于86 nM。
MoreFludarabine, a purine analog, is used in the treatment of hematological malignancies for the inhibition of STAT-1 activation and DNA synthesis. Fludarabine是一种STAT1活性抑制剂和DNA合成抑制剂。
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