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  • Fosbretabulin Disodium EY0295

    Combretastatin A4 disodium phosphate (CA4DP; CA4P), a fluorescent, water-soluble vascular disrupting agent (VDAs), is the pro-drug of CA4 able to induce vascular shutdown within tumors. Fosbretabulin Disodium是微管去稳定剂，能靶向损伤血管。

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  • RO4929097 EY0299

    RO4929097是一种γ secretase抑制剂，IC50为4 nM，抑制Aβ40和Notch的细胞加工，EC50分别为14 nM和5 nM。

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  • AT7867 EY0267

    AT7867是一种有效的，ATP竞争性的Akt1/2/3和p70S6K/PKA抑制剂，IC50分别为32 nM/17 n/47 nM和85 nM/20 nM，对AGC激酶家族以外几乎没有抑制活性。

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  • IWP-2 EY0270

    IWP-2抑制Wnt信号和分泌，IC50为27 nM，选择性抑制Porcn介导的Wnt棕榈酰化，一般不影响Wnt/β-catenin，且对Wnt刺激的细胞反应没有影响。

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  • Go6976 EY0278

    Go6976 is a potent protein kinase C (PKC) inhibitor (IC50 = 7.9 nM), selectively inhibits PKCα, and PKCβ1 (IC50 values are 2.3 and 6.2 nM respectively).

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