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  • Vinorelbine Tartrate EY1793

    Vinorelbine ditartrate (长春瑞滨双酒石酸盐; KW-2307) 是抗有丝分裂剂,能抑制Hela细胞增殖,IC50为1.25 nM。

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  • Betulinic acid EY1794

    Natural triterpenoid that displays anti-HIV and antitumor activity. Induces the production of reactive oxygen species (ROS) and activates NF-κB. Exhibits GPBA receptor agonist activity (EC50 = 1.04 μM).

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  • Desvenlafaxine EY1795

    Desvenlafaxine是5-羟色胺(5-HT)和去甲肾上腺素(NE)重吸收抑制剂,Ki为40.2 nM和558.4 nM。

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  • KPT-185 EY1798

    KPT-185 is an orally bioavailable selective inhibitor of CRM1 amd displayes potent antiproliferative properties at submicromolar concentrations (IC50 values:100-500nM), induced apoptosis (average 5-fold increase), cell-cycle arrest, and myeloid differentiation in AML cell lines and patient blasts.

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  • ASP3026 EY1799

    ASP3026是高活性ALK抑制剂,IC50为3.5 nM。

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