Firategrast是口服有效的整合素α4β1/α4β7小分子拮抗剂。
MoreFAK Inhibitor 14 is a selective focal adhesion kinase (FAK) inhibitor, it prevents FAK autophosphorylation at Y397 (IC50 = 1μM).
MoreML167 is the first highly selective inhibitor of of Cdc2-like kinase 4 (Clk4) with an IC50 of 136 nM for Clk4, >10-fold selectivity for closely related kinases Clk1-3 and Dyrk1A/1B, and minimal activity against a panel of other kinases tested.
MoreSkepinone-L是一种选择性p38 MAPK抑制剂,IC50为5 nM。
MoreBMS-265246是CDK1/2抑制剂,对CDK1/cyclin B和CDK2/cyclin E的IC50分别为6 nM和9 nM。
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