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  • Enzalutamide EY0026

    Enzalutamide, an AR signaling inhibitor, is effective for bicalutamide-resistant tumors and has been used in metastatic castration-resistant prostate cancer. Enzalutamide (MDV3100)是一种雄激素受体(AR)拮抗剂，IC50为36 nM。

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  • Docetaxel EY0027

    Docetaxel, a cytotoxic antimicrotuble agent, is frequently administrated as a first line treatment for prostate cancers. Docetaxel，一种紫杉醇类似物，通过结合到稳定的微管来抑制微管解聚。

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  • SAHA EY0003

    Vorinostat (SAHA, MK0683)是一种I和II类组蛋白去乙酰化酶(HDAC)抑制剂，IC50小于86 nM。

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  • Fludarabine EY0005

    Fludarabine, a purine analog, is used in the treatment of hematological malignancies for the inhibition of STAT-1 activation and DNA synthesis. Fludarabine是一种STAT1活性抑制剂和DNA合成抑制剂。

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  • Danazol EY2829

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