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  • Honokiol EY0371

    Honokiol, a low molecular weight natural product isolated from the bark of magnolia officinalis, possesses potent anticancer activities which is chiefly via the inhibition of AKT and mitogen-activated protein kinase (MAPK) phosphorylation. Honokiol是木兰的有效成分,抑制Akt磷酸化,且促进ERK1/2磷酸化。

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  • MG-101 EY0341

    MG-101是一种有效的半胱氨酸蛋白酶抑制剂, 作用于钙蛋白酶I, 钙蛋白酶II, 组织蛋白酶B, 和组织蛋白酶L, Ki值分别为190 nM , 220 nM, 150 nM, 500 pM.

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  • Flavopiridol HCl EY0346

    Flavopiridol与ATP竞争抑制CDK1,CDK2,CDK4和CDK6,IC50为40 nM。Flavopiridol还具有EGFR和PKA抑制性。

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  • TGX-221 EY0347

    TGX-221, a novel, potent, isoform-specific, and cell-permeable small molecule inhibitor of PI3Kβ, is critical for cell growth, proliferation, and tumorigenesis of PTEN-deficient tumor cells. TGX-221是可通透细胞的PI3K p110β选择性抑制剂。

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  • OAC1 EY0349

    OAC1是转录因子Oct4活化剂,提高iPSC的重编程效率和编程过程中的加速。

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