PF-3084014 is a reversible, noncompetitive, and selective γ-secretase inhibitor with IC50 of 6.2 nM.
MoreTangeretin, a flavonoid from citrus fruit peels, has been proven to play an important role in anti-inflammatory responses and neuroprotective effects in several disease models, and was also selected as a Notch-1 inhibitor.
MoreLY3039478 is a novel and potent Notch inhibitor.
MoreTocilizumab is an anti-interleukin-6 receptor (IL-6R) monoclonal antibody, currently approved for the treatment of systemic juvenile idiopathic arthritis (sJIA) and rheumatoid arthritis.
MoreTrastuzumab, an anti- ERBB2 (HER2 or HER-2/neu) humanized monoclonal antibody, is used to treat “HER2-positive” tumors.
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