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Etanercept, a TNFα receptor Fc fusion protein that binds to IgG1, is used for the treatment of rheumatic disease and psoriasis.
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Evolocumab (Repatha, AMG 145) is a fully human monoclonal antibody against PCSK9, significantly reduces low-density lipoprotein-cholesterol (LDL-C) levels.
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Gemtuzumab, a humanized anti-CD33 monoclonal antibody, is used to treat patients with previously untreated or recurrent acute myelogenous leukemia (AML).
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Golimumab is a fully human anti-TNF IgG1κ monoclonal antibody that acts principally by targeting and neutralizingTNF to prevent inflammation and destruction of cartilage and bone.
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Ibritumomab tiuxetan, a radioactive yttrium-90-conjugated monoclonal antibody to CD20, has demonstrated therapeutic efficacy with durable responses and allows delivery of ionizing radiation directly to the tumor site, while minimizing toxicity to normal tissue.
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